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  • Master Tutor
  • Name (Pinyin):

    fengtiantian
  • School/Department:

    化学与化工学院
  • Business Address:

    陕西省西安市鄠邑区草堂寺景区草寺东路学府城6号楼102B
  • Gender:

    Female
  • Contact Information:

    邮箱:fengtt168@xauat.edu.cn; fengtiantianwork@163.com;
  • Degree:

    Doctoral degree
  • Status:

    Employed
  • Academic Titles:

    西安建筑科技大学,化学与化工学院,副教授
  • Alma Mater:

    海南大学
  • Discipline:

    Applied Chemistry

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Ultrasensitive Detection of Aqueous Uranyl Based on Uranyl-Triggered Protein Photocleavage

  • Release time:2024-10-22
  • Hits:

  • Impact Factor:

    16.9
  • Journal:

    Angewandte Chemie International Edition
  • Abstract:

    Abstract The detection of environmental uranyl is attracting increasing attention. However, the available detection strategies mainly depend on the selective recognition of uranyl, which is subject to severe interference by coexisting metal ions. Herein, based on the unique uranyl-triggered photocleavage property, the protein BSA is labelled with fluorescent molecules that exhibit an aggregation-induced emission effect for uranyl detection. Uranyl-triggered photocleavage causes the separation of the fluorescent-molecule-labelled protein fragments, leading to attenuation of the emission fluorescence, which is used as a signal for uranyl detection. This detection strategy shows high selectivity for uranyl and an ultralow detection limit of 24 pM with a broad detection range covering five orders of magnitude. The detection method also shows high reliability and stability, making it a promising technique for practical applications in diverse environments.
  • First Author:

    Tiantian Feng, Yihui Yuan*, Shilei Zhao, Lijuan Feng, Bingjie Yan, Meng Cao, Jiacheng Zhang, Wenyan Sun, Ke Lin, Ning Wang*
  • Indexed by:

    Journal paper
  • Translation or Not:

    no
  • Included Journals:

    SCI
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