Ultrasensitive Detection of Aqueous Uranyl Based on Uranyl-Triggered Protein Photocleavage
发布时间：2024-10-22
点击次数：
- 影响因子：
- 16.9
- 发表刊物：
- Angewandte Chemie International Edition
- 摘要：
- Abstract The detection of environmental uranyl is attracting increasing attention. However, the available detection strategies mainly depend on the selective recognition of uranyl, which is subject to severe interference by coexisting metal ions. Herein, based on the unique uranyl-triggered photocleavage property, the protein BSA is labelled with fluorescent molecules that exhibit an aggregation-induced emission effect for uranyl detection. Uranyl-triggered photocleavage causes the separation of the fluorescent-molecule-labelled protein fragments, leading to attenuation of the emission fluorescence, which is used as a signal for uranyl detection. This detection strategy shows high selectivity for uranyl and an ultralow detection limit of 24 pM with a broad detection range covering five orders of magnitude. The detection method also shows high reliability and stability, making it a promising technique for practical applications in diverse environments.
- 第一作者：
- Tiantian Feng, Yihui Yuan*, Shilei Zhao, Lijuan Feng, Bingjie Yan, Meng Cao, Jiacheng Zhang, Wenyan Sun, Ke Lin, Ning Wang*
- 论文类型：
- 期刊论文
- 是否译文：
- 否
- 收录刊物：
- SCI