The Synthesis and Spectral Properties of Some New MonomethineCyanine Dyes for Live Cell Imaging
发布时间：2024-08-09
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- 所属单位：
- 化学与化工学院
- 发表刊物：
- Bull. Korean Chem. Soc
- 关键字：
- 中文关键字：合成；一甲川菁染料，紫外-可见吸收光谱，活细胞成像，英文关键字：Synthesis; Monomethine cyanine dyes;UV–Vis;Live ce
- 摘要：
- Four monomethine cyanine dyes were synthesized and their structures were confirmed by 1H NMR, IR, UV–Vis, and HRMS. Their spectral properties were studied. It could be found that the λmax of the dyes was shorter in the protonic solvents compared with that in the nonprotonic solvents. Moreover, the λmax shows a hypsochromic shift with the increasing polarity of the solvents. The interactions of four dyes with DNA were also studied. The results showed that the fluorescence intensities of the dyes 3a and 3b took place a qualitative change in the presence of DNA compared with the free dyes. The dyes used as cellular imaging agents were researched. The results indicated that the dye 3b could penetrate the live cell membrane.
- 备注：
- 付义乐
- 合写作者：
- 杨清翠,张国,董社英,翟鑫,王兰英
- 第一作者：
- 付义乐
- 论文类型：
- 期刊论文
- 卷号：
- 卷：36
- 期号：
- 期：
- 页面范围：
- 页：1-7
- 是否译文：
- 否
- 发表时间：
- 2015-01-01